View Article Google Scholar 8. Knockdown of Id1 slightly decreased the proliferation of MM cell. B Expression of Id1 was checked by immunostaining. S12and partially rescued Dorsomorphin inhibition of anchorage-independent colony formation Fig. Expression plasmids of truncated Smad1-MH2 were constructed by cloning the indicated sequence into pEGFP vector using the following primers:
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Knockdown of Id1 slightly decreased the proliferation of MM cell.
Finally, we determined the efficacy of Dorsomorphin in inhibiting in vivo tumor growth of KMM cells. Statistical analysis Data were analyzed by Student's t test. Cells were harvested at the indicated times. Sh LANA was previously reported . Ids were indispensable driving forces for KSHV-induced tumorigenesis Id proteins, especially Id1, are able to promote cell proliferation and cell cycle progression.